Acetylcysteine for Acetaminophen Poisoning New England Journal of Medicine Tylenol, Autism, And The Glutathione Connection OC Integrative Medicine Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Acetaminophen Overdose Reveals PAR4 as a Low Expressing but Potent Receptor on the Hepatic Endothelium in Mice Arteriosclerosis, Thrombosis, and Vascular Biology Inflammasome activation as a key driver of acetaminophen induced hepatotoxicity: Mechanisms and emerging therapeutics EurekAlert!