Glutathione Synthesis and Turnover in the Human Erythrocyte Journal of Biological Chemistry In RBCs, NADPH are produced exclusively via HMP shunt by the action of G6PD and are responsible to maintain membrane integrity preventing premature destruction. That is why G6PD deficient RBCs are Frontiers Glutathione: A Samsonian life sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation L glutamine for sickle cell disease: more than reducing redox Annals of Hematology Springer Nature Link Glutathione, Erythrocytes Doctor's Data Kit Brighter Life Labs