How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin Enhancement of collagen deposition and cross linking by coupling lysyl oxidase with bone morphogenetic protein 1 and its application in tissue engineering Scientific Reports Can GHK Cu Copper Peptide Tighten Skin After Weight Loss? Site specific cross linking of collagen peptides by lysyl advanced glycation endproducts Chemical Communications (RSC Publishing) Lysine Hydroxylation and Cross Linking of Collagen Springer Nature Link