Central Line Dressing Change, , Central lines are at a high risk of serious infection. Proper central line care is a key to preventing these central line associated bloodstream infections called Central Line Dressing Change and Sterilization Best Practices Peripherally Inserted Central Catheter (PICC Line) Peripherally Inserted Central Catheter (PICC) Dressing Management Clinical Guideline Text Discharge Instructions: Changing the Dressing on Your Midline Catheter