PeerJ The function and mechanisms of action of lysyl oxidase like 3 (LOXL3) in cancers How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin Lysyl oxidase (LOX) mediates intermolecular crosslinks between Download Scientific Diagram Glycation of type I collagen selectively targets the same helical domain lysine sites as lysyl oxidasemediated cross linking Journal of Biological Chemistry Full article: Enzymatic cross linking of collagens in organ fibrosis resolution and assessment