Glycerol as a precursor for hepatic de novo glutathione synthesis in human liver ScienceDirect Hepatic Glutathione Synthesis: The Liver's Antioxidant Powerhouse Glutathione (GSH) is the most abundant intracellular antioxidantand the liver is its primary production site. Through a tightly regulated, ATP dependent pathway, hepatocytes Dysregulation of glutathione synthesis in liver disease ScienceDirect Liver 3 Glutathione in liver diseases and hepatotoxicity. Semantic Scholar